The Genomics Core is focused on gathering genome, transcriptome, epigenome and metagenome information for investigators. Our mission is to make these complex technologies accessible and biologically interpretable for clinical and basic research scientists. The Genomics Core enables investigators with little experience in sample preparation, quality control or analysis to interrogate the genome. To facilitate this, we have developed general but complete wet-lab and bioinformatics analysis pipelines to accommodate standard needs and enable most genomewide investigations. For more sophisticated or custom designs, we work actively in collaboration with other Cedars-Sinai cores and resources to facilitate investigations.
The Research Bioinformatician III (RBIII) w orks independently but in close cooperation and consultation with Research Scientists, PI, Research Nurses, and Research Coordinators. The Research Bioinformatician III will interact with investigators to understand scientific questions , define the scope of work and propose an analytical plan with a time estimate for its completion. The RBIII will work independently and with bioinformatics faculties to determine future bioinformatics needs, and helps to develop tools and pipelines as necessary to keep pace with rapid advances in sequencing technol ogy. The Bioinformatician III will also identify, evaluate, and incorporate relevant algorithms and software by reviewing pertinent literatures and develop and maintain software based on current projects and in anticipation of long-term needs.
In addition the RBIII will also be responsible for the following:
Provides general bioinformatics analysis support for omic projects and mainly responsible for data analysis and software compilations including next generation sequence alignment, polymorphism identification, expression analysis, and visualization tools and browsers.
Summarizes data analyses results in the form suitable as the basis for the first draft of written reports, and makes preliminary interpretations of the data.
Be proficient and maintain proficiency in development, testing, and maintenance of modular software pipelines for genome sequencing, assembly, annotation, metagenomic analysis, and genotyping using high-throughput sequencing platforms including 454, Illumina, and Pacific Biosciences.
Manages data including loading and querying data from database systems, downloading omic data from public repositories, and transforming data to the necessary formats
Familiar with medical and biological terminologies, bioinformatics resources, and national biological databases, Ready to provide solutions for investigator's problems through data mining and extraction
In a consultation setting, interact with investigators to understand scientific questions. Define the scope of work and propose an analytical plan with a time estimate for its completion.
Identify, evaluate, and incorporate relevant algorithms and software pipelines by reviewing pertinent literatures in bioinformatics and computational biology
Provide bioinformatics expertise in the design of experiments and studies, including research proposal development, sample size determination, and plans for interim reviews and final analysis
Develop tools and pipelines as necessary to keep pace with rapid advances in sequencing technology.
Interact with and support other bioinformatics colleagues in pursuing excellence in Research and Education, that is, the generation of new ideas and concepts, and their dissemination.
Educate others about bioinformatics and computational biology through mentoring of and teaching colleagues, investigators, fellows, and graduate students. Be capable of organizing and teaching formal bioinformatics courses, inter-disciplinary courses, continuing education courses, and seminars.
Providing healthcare for more than 100 years, Cedars-Sinai has evolved into one of the most dynamic and highly renowned medical centers in the world. Along with caring for patients, Cedars-Sinai is a hub for biomedical research and a training center for future physicians and other healthcare professionals. This attracts exceptional talent to Cedars-Sinai, including world-renowned physician-scientists who seek a place where they can both conduct research and see patients--the ideal formula for discovery and its translation into cures. Our patients benefit from access to doctors at the top of their fields, and our researchers have an ideal community in which to study the impact of healthcare challenges, and reflect that knowledge in their research. The greater Los Angeles area in which Cedars-Sinai resides possesses unparalleled cultural and ethnic diversity which offers outstanding opportunities for translational and clinical research and a dynamic environment for medical education.Although community based, Cedars-Sinai is a major t...eaching hospital affiliated with the David Geffen School of Medicine at the University of California, Los Angeles (UCLA). Cedars-Sinai has highly competitive graduate medical education programs in more than 50 specialty and subspecialty areas, a graduate program in biomedical sciences and translational medicine, a clinical scholars program directed towards junior physicians with aspirations to become clinical scientists, and post graduate training opportunities.There are more than 250 full-time faculty members at Cedars-Sinai. The voluntary medical staff, comprised of more than 2,200 specialty board-certified or board-qualified physicians, represent all of the specialties and subspecialties and collaborate with full-time medical staff in the teaching responsibilities of the graduate medical education programs.